Anti-IL31RA抗体(ab113498)

概述

  • 产品名称Anti-IL31RA抗体
    参阅全部 IL31RA 一抗
  • 描述
    兔多克隆抗体to IL31RA
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 91-378 of Human IL31RA (BC110490).

  • 阳性对照
    • Jurkat cell lysate, Human fetal liver, fetal kidney, fetal spleen and fetal colon lysates; Human fetal prostate tissue.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab113498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 83 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity.
  • 组织特异性Expressed at low levels in testis, ovary, brain, prostate, placenta, thymus, bone marrow, trachea and skin. Detected in all of the myelomonocytic lineage. Expressed in CD14-and CD56-positive blood cells and by macrophages (at protein level).
  • 序列相似性Belongs to the type I cytokine receptor family. Type 2 subfamily.
    Contains 5 fibronectin type-III domains.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Class I cytokine receptor antibody
    • CRL 3 antibody
    • CRL antibody
    • CRL3 antibody
    • Cytokine receptor like 3 antibody
    • Cytokine receptor-like 3 antibody
    • GLM R antibody
    • GLM-R antibody
    • GLMR antibody
    • Gp130 like monocyte receptor antibody
    • GP130 like receptor antibody
    • Gp130-like monocyte receptor antibody
    • Gp130-like receptor antibody
    • GPL antibody
    • HGLM R antibody
    • HGLM-R antibody
    • HGLMR antibody
    • IL 31 receptor subunit alpha antibody
    • IL 31R subunit alpha antibody
    • IL 31RA antibody
    • IL-31 receptor subunit alpha antibody
    • IL-31R subunit alpha antibody
    • IL-31R-alpha antibody
    • IL-31RA antibody
    • IL31 receptor subunit alpha antibody
    • IL31R subunit alpha antibody
    • IL31R_HUMAN antibody
    • IL31RA antibody
    • Interleukin 31 receptor A antibody
    • interleukin 31 receptor subunit alpha antibody
    • Interleukin-31 receptor subunit alpha antibody
    • MGC125346 antibody
    • PLCA 2 antibody
    • PLCA2 antibody
    • PRO21384 antibody
    • Soluble type I cytokine receptor CRL3 antibody
    • ZcytoR17 antibody
    see all

Anti-IL31RA antibody 图像

  • All lanes : Anti-IL31RA antibody (ab113498) at 1/500 dilution

    Lane 1 : Jurkat cell lysate
    Lane 2 : Human fetal liver lysate
    Lane 3 : Human fetal kidney lysate
    Lane 4 : Human fetal spleen lysate
    Lane 5 : Human fetal colon lysate


    Predicted band size : 83 kDa
  • ab113498, at 1/100, staining IL31RA in Formalin-fixed, Paraffin-embedded Human fetal prostate tissue by Immunohistochemistry.

Anti-IL31RA antibody (ab113498)参考文献

ab113498 has not yet been referenced specifically in any publications.

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Abreviews
Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - whole (liver, brain, bone merrow)
Loading amount 125 µg
Specification liver, brain, bone merrow
Treatment Folfox for 24h and control (Not treated)
Gel Running Conditions Reduced Denaturing (4-15)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 20% · Temperature: 24°C
Username

Dr. Ella Fremder

Verified customer

提交于 Nov 16 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"