概述

  • 产品名称Anti-IL31抗体
    参阅全部 IL31 一抗
  • 描述
    兔多克隆抗体to IL31
  • 特异性ab37157 recognises Interleukin 31 (IL31).
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Synthetic peptide, corresponding to a 16 amino acid sequence from near the N terminal of Mouse IL-31 protein

  • 阳性对照
    • RAW264.7 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab37157 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2.5 - 5 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 18 kDa).Can be blocked with Mouse IL31 peptide (ab39776).
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
  • 组织特异性Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 形式Amino acids 1-23 are a signal peptide.
  • 别名
    • IL 31 antibody
    • IL-31 antibody
    • IL31 antibody
    • IL31_HUMAN antibody
    • Interleukin 31 antibody
    • Interleukin-31 antibody
    see all

Anti-IL31 antibody 图像

  • Lane 1 : Anti-IL31 antibody (ab37157) at 2.5 µg/ml
    Lane 2 : Anti-IL31 antibody (ab37157) at 5 µg/ml
    Lane 3 : Anti-IL31 antibody (ab37157) at 10 µg/ml

    Lane 1 : RAW264.7 cell lysate
    Lane 2 : RAW264.7 cell lysate
    Lane 3 : RAW264.7 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 18 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
  • ab37157 at 10µg/ml staining IL-31 in rat skeletal muscle tissue by IHC 

Anti-IL31 antibody (ab37157)参考文献

This product has been referenced in:
  • Niyonsaba F  et al. Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol 184:3526-34 (2010). Read more (PubMed: 20190140) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. The image was labelled incorrectly, all lanes were blotted with a concentration of antobody 10 ug/ml. We are updating the datasheet now, thank you for bringing this error to our attention.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"