概述

  • 产品名称Anti-IL28 Receptor alpha抗体
    参阅全部 IL28 Receptor alpha 一抗
  • 描述
    兔多克隆抗体to IL28 Receptor alpha
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 72 - 121 (EECAGTKELL CSMMCLKKQD LYNKFKGRVR TVSPSSKSPW VESEYLDYLF) of IL28 Receptor alpha (NP_775087)

  • 阳性对照
    • Jurkat cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab83865 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa.Can be blocked with IL28 Receptor alpha peptide (ab195307). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain.
  • 细胞定位Membrane; Single-pass type I membrane protein
  • 数据库链接
  • 别名
    • Class II cytokine receptor CRF2/12 antibody
    • CRF2-12 antibody
    • CRF2/12 antibody
    • Cytokine receptor class-II member 12 antibody
    • Cytokine receptor family 2 member 12 antibody
    • IFN lambda R1 antibody
    • IFN-lambda receptor 1 antibody
    • IFNLR antibody
    • IFNLR1 antibody
    • IL-28 receptor subunit alpha antibody
    • il-28r1 antibody
    • IL28R alpha antibody
    • IL28RA antibody
    • Interferon lambda receptor antibody
    • Interferon lambda receptor 1 antibody
    • interleukin 28 alpha receptor antibody
    • interleukin 28 receptor A antibody
    • Interleukin 28 receptor alpha chain antibody
    • interleukin 28 receptor, alpha (interferon, lambda receptor) antibody
    • Interleukin 28 receptor, alpha antibody
    • interleukin or cytokine receptor 2 antibody
    • Interleukin-28 receptor subunit alpha antibody
    • LICR2 antibody
    • Likely interleukin or cytokine receptor 2 antibody
    see all

Anti-IL28 Receptor alpha antibody 图像

  • Anti-IL28 Receptor alpha antibody (ab83865) at 1 µg/ml (5% skim milk / PBS) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 57 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 35 kDa. We are unsure as to the identity of these extra bands.

Anti-IL28 Receptor alpha antibody (ab83865)参考文献

This product has been referenced in:
  • Egli A  et al. Immunomodulatory Function of Interleukin 28B During Primary Infection With Cytomegalovirus. J Infect Dis N/A:N/A (2014). WB . Read more (PubMed: 24620020) »

See 1 Publication for this product

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