概述

  • 产品名称
  • 描述
    兔多克隆抗体to IL26
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region between amino acid 94 - 124 from the central region of Human il26 (UniProt ID: Q9NPH9).

  • 阳性对照
    • HL60 cell line lysates

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab102977 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab102977 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 20 kDa.

靶标

  • 功能
    May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
  • 组织特异性
    Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T cells including Th17 inflammatory T cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level).
  • 序列相似性
    Belongs to the IL-10 family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AK155 antibody
    • IL 26 antibody
    • IL-26 antibody
    • IL26 antibody
    • IL26_HUMAN antibody
    • Interleukin 26 antibody
    • Interleukin-26 antibody
    • Protein AK155 antibody
    see all

图片

  • Anti-IL26 antibody (ab102977) at 1/100 dilution + HL60 cell line lysates at 35 µg

    Predicted band size : 20 kDa

实验方案

文献

This product has been referenced in:
  • Che KF  et al. Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines. Mol Med 23:N/A (2017). WB ; Human . Read more (PubMed: 28853490) »
  • Reemann P  et al. Expression of class II cytokine genes in children's skin. Acta Derm Venereol 94:386-92 (2014). Read more (PubMed: 24284923) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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