Anti-IL22 RA2抗体[MM0397-6G47] (ab90937)

概述

  • 产品名称
    Anti-IL22 RA2抗体[MM0397-6G47]
    参阅全部 IL22 RA2 一抗
  • 描述
    小鼠单克隆抗体[MM0397-6G47] to IL22 RA2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length Human IL22 RA2

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
  • 克隆
    单克隆
  • 克隆编号
    MM0397-6G47
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab90937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 31 kDa.

靶标

  • 功能
    Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
    Isoform 1 may play a role in establishing and maintaining successful pregnancy.
  • 组织特异性
    Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.
  • 序列相似性
    Belongs to the type II cytokine receptor family.
    Contains 3 fibronectin type-III domains.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IL 22BP antibody
    • IL 22RA2 antibody
    • IL22RA2 antibody
    • Class II cytokine receptor antibody
    • CRF2 10 antibody
    • CRF2 S1 antibody
    • CRF2-10 antibody
    • CRF2-S1 antibody
    • CRF2X antibody
    • Cytokine receptor class II member 10 antibody
    • Cytokine receptor class-II member 10 antibody
    • Cytokine receptor family 2 member 10 antibody
    • Cytokine receptor family type 2 antibody
    • Cytokine receptor family type 2 soluble 1 antibody
    • I22R2_HUMAN antibody
    • IL 22 receptor subunit alpha 2 antibody
    • IL 22R alpha 2 antibody
    • IL-22 receptor subunit alpha-2 antibody
    • IL-22BP antibody
    • IL-22R-alpha-2 antibody
    • IL-22RA2 antibody
    • IL22BP antibody
    • IL22R alpha 2 antibody
    • Il22ra2 antibody
    • Interleukin 22 binding protein antibody
    • Interleukin 22 Receptor alpha 2 antibody
    • Interleukin-22 receptor subunit alpha-2 antibody
    • Interleukin-22-binding protein antibody
    • MGC150509 antibody
    • MGC150510 antibody
    • soluble 1 antibody
    • ZcytoR16 antibody
    see all

实验方案

文献

ab90937 has not yet been referenced specifically in any publications.

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