概述

  • 产品名称
  • 描述
    山羊多克隆抗体to IL22
  • 经测试应用
    适用于: ELISA, ICC, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Dog
  • 免疫原

    Synthetic peptide:

    LKDTVKKLGESGEIKAIGELDLLFMSLRNA

    , corresponding to C terminal amino acids 148-177 of Human IL22.

  • 阳性对照
    • Human spleen and tonsil.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: 140mM Sodium chloride, 10mM Potassium phosphate. pH 7.2
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab18498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/100000.
ICC 1/300.
IHC-P Use at an assay dependent dilution. PubMed: 21182091

靶标

  • 功能
    Cytokine that contributes to the inflammatory response in vivo.
  • 序列相似性
    Belongs to the IL-10 family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cytokine Zcyto18 antibody
    • IL 10 related T cell derived inducible factor antibody
    • IL 21 antibody
    • IL 22 antibody
    • IL D110 antibody
    • IL TIF antibody
    • IL-10-related T-cell-derived-inducible factor antibody
    • IL-22 antibody
    • IL-TIF antibody
    • IL21 antibody
    • Il22 antibody
    • IL22_HUMAN antibody
    • ILD110 antibody
    • ILTIF antibody
    • Interleukin 10 related T cell derived inducible factor antibody
    • interleukin 21 antibody
    • Interleukin 22 antibody
    • Interleukin-22 antibody
    • MGC79382 antibody
    • MGC79384 antibody
    • TIFa antibody
    • TIFIL 23 antibody
    • TIFIL23 antibody
    • UNQ3099/PRO10096 antibody
    • zcyto18 antibody
    see all

图片

  • ab18498 (1/300) used for the immunohistochemical detection of human C-terminal IL22 on a paraffin embedded section of human tonsil.

文献

This product has been referenced in:
  • Johnson JR  et al. IL-22 contributes to TGF-ß1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells. Respir Res 14:118 (2013). IHC . Read more (PubMed: 24283210) »
  • Takenaka N  et al. Overexpression of phospholipase Ce in keratinocytes upregulates cytokine expression and causes dermatitis with acanthosis and T-cell infiltration. Eur J Immunol 41:202-13 (2011). IHC-P ; Mouse . Read more (PubMed: 21182091) »

See all 2 Publications for this product

客户评价及客户问答

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Rat Tissue sections (Inflammed Colon, Normal Spleen)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Citrate pH6
Permeabilization
No
Specification
Inflammed Colon, Normal Spleen
Fixative
Formaldehyde
Username

Abcam user community

Verified customer

提交于 Aug 19 2015

Thank you for contacting Abcam.

I can see no reason why you cannot use a fluorescently tagged secondary antibody with these primariesin your IHC-P experiments (for ab5690, there is even an IHC-Fr image, where they used a fluorescent secondary...

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I am very pleased to hear you would like to accept our offer and test ab18498 in horse, WB and flow cytometry. This code will give you 1 free PRIMARY...

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I am sorry that this antibody did not perform as stated on the datasheet. If payment has already been made on the original order and you wish to receive a refund, please ask your purchasing department to contact our...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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