Anti-IL21抗体(ab18495)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to IL21
  • 特异性
    Peptide sequence is < 50 % identical to other interleukins in this region and is therefore not expected to cross-react.
  • 经测试应用
    适用于: ELISA, ICCmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    CDSYEKKPPKEFLERFKSLLQKMIHQHLS

    , corresponding to C terminal amino acids 118-146 of Human IL21.

  • 阳性对照
    • Human spleen cells.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: 1mg/ml BSA, 140mM Sodium chloride, 10mM Potassium phosphate. pH 7.2
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab18495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/100000.
ICC 1/500.

靶标

  • 功能
    Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
  • 组织特异性
    Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.
  • 序列相似性
    Belongs to the IL-15/IL-21 family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CVID11 antibody
    • IL 21 antibody
    • IL-21 antibody
    • Il21 antibody
    • IL21_HUMAN antibody
    • Interleukin 21 antibody
    • Interleukin-21 antibody
    • interleukin-21 isoform antibody
    • Interleukin21 antibody
    • OTTHUMP00000164088 antibody
    • Za11 antibody
    see all

文献

ab18495 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your email. These two antibodies have not been tested together in a sandwich ELISA and sensitivity information is not available. However, both do detect different regions of human IL21. We do have a general sandwich ELISA protocol which y...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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