Anti-IL-20R2抗体[20RNTC] (ab95824)
Key features and details
- Rat monoclonal [20RNTC] to IL-20R2
- Suitable for: Flow Cyt, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG2a
概述
-
产品名称
Anti-IL-20R2抗体[20RNTC]
参阅全部 IL-20R2 一抗 -
描述
大鼠单克隆抗体[20RNTC] to IL-20R2 -
宿主
Rat -
特异性
ab95824 recognizes Mouse and Human IL-20R2 in either of its two heterodimeric complexes formed by pairing with IL-20RA or IL-22RA1 -
经测试应用
适用于: Flow Cyt, ICC/IFmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant fragment corresponding to Mouse IL-20R2 (extracellular).
-
阳性对照
- Fixed and permeabilized A375 cells
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: 1% PBS -
Concentration information loading...
-
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
20RNTC -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95824于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use a concentration of 1 - 10 µg/ml.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
|
ICC/IF |
Use a concentration of 1 - 10 µg/ml.
|
说明 |
---|
Flow Cyt
Use a concentration of 1 - 10 µg/ml. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ICC/IF
Use a concentration of 1 - 10 µg/ml. |
靶标
-
功能
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. -
组织特异性
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. -
序列相似性
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 53833 Human
- Entrez Gene: 213208 Mouse
- Omim: 605621 Human
- SwissProt: Q6UXL0 Human
- Unigene: 61232 Human
-
别名
- DIRS1 antibody
- Fibronectin type III domain containing 6 antibody
- FNDC6 antibody
see all
图片
实验方案
数据表及文件
-
Datasheet download
文献 (5)
ab95824 被引用在 5 文献中.
- Lu Z et al. IL-20 promotes cutaneous inflammation and peripheral itch sensation in atopic dermatitis. FASEB J 36:e22334 (2022). PubMed: 35486004
- Wang HH et al. Interleukin-24 protects against liver injury in mouse models. EBioMedicine 64:103213 (2021). PubMed: 33508745
- Weng YH et al. Blocking IL-19 Signaling Ameliorates Allergen-Induced Airway Inflammation. Front Immunol 10:968 (2019). PubMed: 31114590
- He B et al. A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy. PLoS One 8:e56414 (2013). WB ; Mouse . PubMed: 23441190
- Hsing CH et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res 18:713-25 (2012). ICC/IF . PubMed: 22186257