Anti-IL2 Receptor beta抗体[TM-beta1] (Phycoerythrin) (ab95774)

概述

  • 产品名称Anti-IL2 Receptor beta抗体[TM-beta1] (Phycoerythrin)
    参阅全部 IL2 Receptor beta 一抗
  • 描述
    大鼠单克隆抗体[TM-beta1] to IL2 Receptor beta (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Rat T cell line expressing Mouse IL2 Receptor beta.

  • 阳性对照
    • Mouse splenocyte suspensions
  • 常规说明


    High affinity binding of IL2 to the IL2 receptor is inhibited by ab95774.

性能

应用

Our Abpromise guarantee covers the use of ab95774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.06-0.125µg for 105-8 cells. A final volume of 100 µL is recommended for staining the cell sample.

靶标

  • 功能Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
  • 序列相似性Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • 结构域The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD122 antibody
    • CD122 antigen antibody
    • High affinity IL 2 receptor beta subunit antibody
    • High affinity IL 2 receptor subunit beta antibody
    • High affinity IL-2 receptor subunit beta antibody
    • IL-2 receptor subunit beta antibody
    • IL-2R subunit beta antibody
    • IL-2RB antibody
    • IL15RB antibody
    • IL2 receptor antibody
    • IL2RB antibody
    • IL2RB_HUMAN antibody
    • Interleukin 2 receptor beta antibody
    • Interleukin-2 receptor subunit beta antibody
    • P70 75 antibody
    • P70-75 antibody
    • P7075 antibody
    • p75 antibody
    see all

Anti-IL2 Receptor beta antibody [TM-beta1] (Phycoerythrin) 图像

  • Staining of C57BL/6 splenocytes with Anti-Mouse NK1.1 APC and 0.06 µg of Rat IgG2b ? Isotype Control PE (left) or 0.06 µg of ab95774 (right).
    Total viable cells were used for analysis.

Anti-IL2 Receptor beta antibody [TM-beta1] (Phycoerythrin) (ab95774)参考文献

This product has been referenced in:
  • French JD  et al. {gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells. Proc Natl Acad Sci U S A 102:14741-6 (2005). Read more (PubMed: 16203967) »

See 1 Publication for this product

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