概述

  • 产品名称Anti-IL2 Receptor beta抗体
    参阅全部 IL2 Receptor beta 一抗
  • 描述
    兔多克隆抗体to IL2 Receptor beta
  • 特异性ab61195 detects endogenous levels of total IL2 Receptor beta protein.
  • 经测试应用适用于: IHC-P, WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic non-phosphopeptide derived from human IL2 Receptor beta around the phosphorylation site of tyrosine 364.

  • 阳性对照
    • Human lung carcinoma tissue and COS7 cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab61195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
WB 1/500 - 1/1000. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).
ELISA 1/20000.

靶标

  • 功能Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
  • 序列相似性Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • 结构域The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD122 antibody
    • CD122 antigen antibody
    • High affinity IL 2 receptor beta subunit antibody
    • High affinity IL 2 receptor subunit beta antibody
    • High affinity IL-2 receptor subunit beta antibody
    • IL-2 receptor subunit beta antibody
    • IL-2R subunit beta antibody
    • IL-2RB antibody
    • IL15RB antibody
    • IL2 receptor antibody
    • IL2RB antibody
    • IL2RB_HUMAN antibody
    • Interleukin 2 receptor beta antibody
    • Interleukin-2 receptor subunit beta antibody
    • P70 75 antibody
    • P70-75 antibody
    • P7075 antibody
    • p75 antibody
    see all

Anti-IL2 Receptor beta antibody 图像

  • ab61195 at 1/50 dilution staining IL2 Receptor beta in human lung carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.
  • All lanes : Anti-IL2 Receptor beta antibody (ab61195) at 1/500 dilution

    Lane 1 : COS7 cell extracts
    Lane 2 : COS7 cell extracts with immunising peptide


    Predicted band size : 61 kDa
    Observed band size : 61 kDa

Anti-IL2 Receptor beta antibody (ab61195)参考文献

This product has been referenced in:
  • Lu ZH  et al. CD25 is a novel marker of hepatic bile canaliculus. Int J Surg Pathol 20:455-61 (2012). ICC/IF ; Human . Read more (PubMed: 22576476) »
  • Cohen CJ  et al. Placenta-specific Expression of the Interleukin-2 (IL-2) Receptor {beta} Subunit from an Endogenous Retroviral Promoter. J Biol Chem 286:35543-52 (2011). WB ; Human . Read more (PubMed: 21865161) »

See all 2 Publications for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Spleen)
Specification Spleen
Fixative Acetone
Permeabilization No
Blocking step Serum as blocking agent for 20 minute(s) · Concentration: 20% · Temperature: 37°C
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提交于 Jul 28 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"