Anti-IL2 Receptor alpha抗体[MRC OX-39] (Biotin) (ab33836)

概述

  • 产品名称Anti-IL2 Receptor alpha抗体[MRC OX-39] (Biotin)
    参阅全部 IL2 Receptor alpha 一抗
  • 描述
    小鼠单克隆抗体[MRC OX-39] to IL2 Receptor alpha (Biotin)
  • 偶联物Biotin
  • 特异性ab33836 recognizes IL2 receptor alpha (55kDa) expressed by activated T cells, but not resting lymphocytes, and by dendritic cells found in the thymus medulla.
  • 经测试应用适用于: Flow Cyt, IHC-Pmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Tissue/ cell preparation: Stimulated Rat T cells

  • 常规说明


    This clone has been described reacting with paraffin-embedded material following PLP fixation (periodate lysine paraformaldehyde). Clone OX 39 has been shown to weakly inhibit the binding of IL2 to Con A stimulated spleen blasts.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab33836 was purified from tissue culture supernatant.
  • Primary antibody说明This clone has been described reacting with paraffin-embedded material following PLP fixation (periodate lysine paraformaldehyde). Clone OX 39 has been shown to weakly inhibit the binding of IL2 to Con A stimulated spleen blasts.
  • 克隆单克隆
  • 克隆编号MRC OX-39
  • 骨髓瘤NS0/1
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab33836 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/10. use 10µl of the suggested working dilution to label 106 cells.



ab18434-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Receptor for interleukin-2.
  • 疾病相关Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • 序列相似性Contains 2 Sushi (CCP/SCR) domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Anti-IL2 Receptor alpha antibody [MRC OX-39] (Biotin) (ab33836)参考文献

This product has been referenced in:
  • Whiteland JL  et al. Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. J Histochem Cytochem 43:313-20 (1995). Read more (PubMed: 7868861) »
  • Paterson DJ  et al. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol Immunol 24:1281-90 (1987). Read more (PubMed: 2828930) »

See all 2 Publications for this product

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Thank you for contacting us. Please find below the list of the Abcam IL2 receptor alpha antibodies which have been tested in Rat (IL2 receptor alpha antibodies are also known as CD25 antibodies http://www.abcam.com/assets/popups/alternative-names.h...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"