概述

  • 产品名称Anti-IL2 Receptor alpha抗体[B-G3]
    参阅全部 IL2 Receptor alpha 一抗
  • 描述
    小鼠单克隆抗体[B-G3] to IL2 Receptor alpha
  • 特异性This antibody recognises both soluble and membrane bound human IL2 Receptor alpha chain.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue/ cell preparation - Human PHA activated T cells.

  • 阳性对照
    • PHA activated lymphocytes
  • 常规说明


    This antibody has no effect in Mixed Lymphocyte Culture.

性能

应用

Our Abpromise guarantee covers the use of ab27308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Receptor for interleukin-2.
  • 疾病相关Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • 序列相似性Contains 2 Sushi (CCP/SCR) domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Anti-IL2 Receptor alpha antibody [B-G3] 图像

  • A typical staining pattern with ab27308 of PHA activated lymphocytes

Anti-IL2 Receptor alpha antibody [B-G3] (ab27308)参考文献

This product has been referenced in:
  • Engert A  et al. Immunotoxins constructed with anti-CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent anti-tumour effects against human Hodgkin cells in vitro and solid Hodgkin tumours in mice. Int J Cancer 49:450-6 (1991). Read more (PubMed: 1917143) »

See 1 Publication for this product

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