Anti-IL18R1抗体[RM0106-7G31] (ab86489)

概述

  • 产品名称
    Anti-IL18R1抗体[RM0106-7G31]
    参阅全部 IL18R1 一抗
  • 描述
    大鼠单克隆抗体[RM0106-7G31] to IL18R1
  • 特异性
    This antibody detects mouse IL18R1 in Western blotting.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse recombinant protein of the extracellular domain of IL18R1

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 纯化说明
    The IgG fraction of culture supernatant was purified by Protein A affinity chromatography
  • 克隆
    单克隆
  • 克隆编号
    RM0106-7G31
  • 同种型
    IgG2
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab86489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 62 kDa.

靶标

  • 功能
    Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.
  • 组织特异性
    Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines.
  • 序列相似性
    Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD218 antigen-like family member A antibody
    • CD218a antibody
    • CDw218a antibody
    • CDw218a antigen antibody
    • IL 1Rrp antibody
    • IL-18R-1 antibody
    • IL-18R1 antibody
    • IL-1Rrp antibody
    • IL1 receptor related protein antibody
    • IL1 receptor-related protein antibody
    • IL18R_HUMAN antibody
    • IL18R1 antibody
    • IL18RA antibody
    • Il18ralpha antibody
    • IL1R-rp antibody
    • IL1RRP antibody
    • Interleukin 18 receptor 1 antibody
    • Interleukin 18 receptor, alpha chain antibody
    • Interleukin-18 receptor 1 antibody
    see all

实验方案

文献

ab86489 has not yet been referenced specifically in any publications.

客户评价及客户问答

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Mouse Tissue sections (mouse brain sections)
Antigen retrieval step
Enzymatic - Buffer/Enzyme Used: pepsin
Specification
mouse brain sections
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 25°C
Fixative
Paraformaldehyde
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提交于 Feb 01 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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