The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明Flow Cyt: Use 20µl for 105-8 cells in a final volume of 100µl..
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.
组织特异性Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines.
序列相似性Belongs to the interleukin-1 receptor family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain.
Staining of normal Human peripheral blood cells with FITC Mouse IgG1, K Isotype Control (blue histogram) or ab93546 (purple histogram). Cells in the granulocyte gate were used for analysis.
Anti-IL18R1 antibody [H44] (FITC) (ab93546)参考文献
This product has been referenced in:
Jegaskanda S et al. Downregulation of interleukin-18-mediated cell signaling and interferon gamma expression by the hepatitis B virus e antigen. J Virol88:10412-20 (2014).
Read more (PubMed: 24872585) »