Anti-IL18R Beta抗体[B-B46] (ab47258)

概述

  • 产品名称Anti-IL18R Beta抗体[B-B46]
    参阅全部 IL18R Beta 一抗
  • 描述
    小鼠单克隆抗体[B-B46] to IL18R Beta
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human IL18R Beta/Fc.

性能

应用

Our Abpromise guarantee covers the use of ab47258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. Use 10 µl to label 106 cells or 100 µl of whole blood.



ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.
  • 组织特异性Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.
  • 序列相似性Belongs to the interleukin-1 receptor family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IL18RAP antibody
    • Accessory protein like antibody
    • Accessory protein-like antibody
    • AcPL antibody
    • CD218 antigen-like family member B antibody
    • CD218b antibody
    • CDw218b antibody
    • I18RA_HUMAN antibody
    • IL 18RAcP antibody
    • IL 1R accessory protein like antibody
    • IL 1R7 antibody
    • IL 1RAcPL antibody
    • IL-18 receptor accessory protein antibody
    • IL-18R-beta antibody
    • IL-18RAcP antibody
    • IL-18Rbeta antibody
    • IL-1R accessory protein-like antibody
    • IL-1R-7 antibody
    • IL-1R7 antibody
    • IL-1RAcPL antibody
    • IL18RAP antibody
    • IL18Rbeta antibody
    • Interleukin 18 receptor accessory protein antibody
    • Interleukin-1 receptor 7 antibody
    • Interleukin-18 receptor accessory protein antibody
    • Interleukin-18 receptor accessory protein-like antibody
    • Interleukin-18 receptor beta antibody
    • Interleukin-18 receptor beta chain antibody
    see all

Anti-IL18R Beta antibody [B-B46] (ab47258)参考文献

ab47258 has not yet been referenced specifically in any publications.

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