Anti-IL17A Receptor抗体[RM0104-10B27] (ab86487)

概述

  • 产品名称Anti-IL17A Receptor抗体[RM0104-10B27]
    参阅全部 IL17A Receptor 一抗
  • 描述
    大鼠单克隆抗体[RM0104-10B27] to IL17A Receptor
  • 特异性This antibody detects mouse IL17A Receptor in Western blotting, but not IL17B Receptor.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse recombinant protein of the extracellular domain of IL17A Receptor

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明The IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
  • 克隆单克隆
  • 克隆编号RM0104-10B27
  • 同种型IgG2
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab86487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 96 kDa.

靶标

  • 功能Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
  • 组织特异性Widely expressed.
  • 疾病相关Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
  • 序列相似性Contains 1 SEFIR domain.
  • 翻译后修饰Glycosylated.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CANDF5 antibody
    • CD217 antibody
    • CD217 antigen antibody
    • CDw217 antibody
    • CTLA8 antibody
    • HIL 17R antibody
    • I17RA_HUMAN antibody
    • IL 17 receptor A antibody
    • IL 17 receptor antibody
    • IL 17RA antibody
    • IL-17 receptor A antibody
    • IL-17RA antibody
    • IL17 antibody
    • IL17A receptor antibody
    • IL17R antibody
    • IL17RA antibody
    • Interleukin 17 receptor A antibody
    • Interleukin-17 receptor A antibody
    • MGC10262 antibody
    see all

Anti-IL17A Receptor antibody [RM0104-10B27] (ab86487)参考文献

ab86487 has not yet been referenced specifically in any publications.

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