Anti-IL17抗体[20B4] (Biotin) (ab123233)

概述

  • 产品名称Anti-IL17抗体[20B4] (Biotin)
    参阅全部 IL17 一抗
  • 描述
    大鼠单克隆抗体[20B4] to IL17 (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: WB, IP, ELISA, Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Recombinant full length Mouse IL17.

  • 阳性对照
    • Mouse splenocytes stimulated with PMA and ionomycin.

性能

应用

Our Abpromise guarantee covers the use of ab123233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 17 kDa.
IP Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab18445-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
  • 组织特异性Restricted to activated memory T-cells.
  • 序列相似性Belongs to the IL-17 family.
  • 翻译后修饰Found both in glycosylated and nonglycosylated forms.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CTLA 8 antibody
    • CTLA-8 antibody
    • CTLA8 antibody
    • Cytotoxic T lymphocyte associated antigen 8 antibody
    • Cytotoxic T lymphocyte associated protein 8 antibody
    • Cytotoxic T lymphocyte associated serine esterase 8 antibody
    • Cytotoxic T-lymphocyte-associated antigen 8 antibody
    • IL 17A antibody
    • IL-17 antibody
    • IL-17A antibody
    • IL17 antibody
    • IL17_HUMAN antibody
    • Il17a antibody
    • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
    • Interleukin 17A antibody
    • Interleukin-17A antibody
    • Interleukin17 antibody
    • Interleukin17A antibody
    • OTTHUMP00000016597 antibody
    • OTTMUSP00000046003 antibody
    see all

Anti-IL17 antibody [20B4] (Biotin) 图像

  • Mouse splenocytes were cultured under Th17 polarizing conditions. They were then left unstimulated (A) or stimulated with PMA and ionomycin in the presence of a protein transport inhibitor (B) and stained for intracellular IL-17A (y axis) using anti-mouse IL-17A clone 20B4.

Anti-IL17 antibody [20B4] (Biotin) (ab123233)参考文献

ab123233 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for your interest in ab79056 Anti-IL17 antibody.

To our knowledge, ab79056 has not been tested in sELISA experiment.
The problem with sELISA is that the coating antibody may block the binding site of the detection antib...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"