Anti-IL13抗体[13A] (Phycoerythrin) (ab95576)

概述

  • 产品名称Anti-IL13抗体[13A] (Phycoerythrin)
    参阅全部 IL13 一抗
  • 描述
    大鼠单克隆抗体[13A] to IL13 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Recombinant full length Mouse IL13 protein.

  • 阳性对照
    • BALB/c splenocytes

性能

应用

Our Abpromise guarantee covers the use of ab95576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.25µg for 105-8 cells. ab154449-Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages.
  • 疾病相关Allergic rhinitis
  • 序列相似性Belongs to the IL-4/IL-13 family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Allergic rhinitis antibody
    • ALRH antibody
    • BHR1 antibody
    • Bronchial hyperresponsiveness 1 (bronchial asthma) antibody
    • IL 13 antibody
    • IL-13 antibody
    • Il13 antibody
    • IL13_HUMAN antibody
    • Interleukin 13 antibody
    • Interleukin-13 antibody
    • MGC116786 antibody
    • MGC116788 antibody
    • MGC116789 antibody
    • NC30 antibody
    • P600 antibody
    see all

Anti-IL13 antibody [13A] (Phycoerythrin) 图像

  • ab95576 at 0.125 µg/test staining IL13 by Flow Cytometry.
    BALB/c splenocytes were cultured for 3 days with plate-bound Anti-Mouse CD3e, soluble Anti-Mouse CD28, Mouse IL2 Recombinant Protein and Mouse IL4 Recombinant Protein. Cells were then harvested and restimulated with PMA and Ionomycin in the presence of monensin for 5 hours. Following restimulation, cells were harvested, surface stained with Anti-Mouse CD4 FITC, fixed and permeabilized, then stained with 0.125 µg of ab95576 (1). The ligand blocking control demonstrates that pre-blocking ab95576 with 1.0 µg of Mouse IL13 Recombinant Protein prior to staining abrogates specific mouse IL13 staining (2).

Anti-IL13 antibody [13A] (Phycoerythrin) (ab95576)参考文献

ab95576 has not yet been referenced specifically in any publications.

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