Anti-IL12 p40 + IL12 p70抗体[B-P40] (ab27379)

概述

  • 产品名称Anti-IL12 p40 + IL12 p70抗体[B-P40]
    参阅全部 IL12 p40 + IL12 p70 一抗
  • 描述
    小鼠单克隆抗体[B-P40] to IL12 p40 + IL12 p70
  • 特异性Recognises both natural and recombinant Human IL12 p40 + p70.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant Human IL12.

  • 常规说明


    No effect on IL12-induced proliferation on PHA and IL2 activated lymphocytes.

性能

应用

Our Abpromise guarantee covers the use of ab27379 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration.

Suitable for intra cytoplasmic flow cytometry.





ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • CLMF p35 antibody
    • CLMF p40 antibody
    • CLMF1 antibody
    • CLMF2 antibody
    • IL12 subunit p35 antibody
    • IL12 subunit p40 antibody
    • IL12A antibody
    • IL12B antibody
    • NKSF antibody
    • NKSF2 antibody
    see all

Anti-IL12 p40 + IL12 p70 antibody [B-P40] (ab27379)参考文献

This product has been referenced in:
  • Verreck FA  et al. Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. Proc Natl Acad Sci U S A 101:4560-5 (2004). Read more (PubMed: 15070757) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"