Anti-IL-12抗体[AP-MAB0853] (ab80682)
Key features and details
- Rat monoclonal [AP-MAB0853] to IL-12
- Suitable for: IP, Neutralising, Flow Cyt, WB
- Reacts with: Mouse
- Isotype: IgG1
概述
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产品名称
Anti-IL-12抗体[AP-MAB0853]
参阅全部 IL-12 一抗 -
描述
大鼠单克隆抗体[AP-MAB0853] to IL-12 -
宿主
Rat -
经测试应用
适用于: IP, Neutralising, Flow Cyt, WBmore details -
种属反应性
与反应: Mouse -
免疫原
Recombinant fragment corresponding to Mouse IL-12.
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常规说明
Endotoxin Level: Extremely low level of LPS (< 0.002EU/µg IgG).ab80682 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯度
Protein A purified -
纯化说明
The IgG fraction of culture supernatant was purified by Protein A affinity chromatography. -
Primary antibody说明
ab80682 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat). -
克隆
单克隆 -
克隆编号
AP-MAB0853 -
同种型
IgG1 -
研究领域
相关产品
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Conjugation kits
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab80682于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IP |
Use at an assay dependent concentration.
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Neutralising |
Use at an assay dependent concentration.
Neutralizes the bioactivity of natural or recombinant IL12 both in vivo and in vitro. |
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Flow Cyt |
Use at an assay dependent concentration.
ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
WB |
Use at an assay dependent concentration.
|
说明 |
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IP
Use at an assay dependent concentration. |
Neutralising
Use at an assay dependent concentration. Neutralizes the bioactivity of natural or recombinant IL12 both in vivo and in vitro. |
Flow Cyt
Use at an assay dependent concentration. ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. -
序列相似性
Belongs to the IL-6 superfamily. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 16159 Mouse
- Entrez Gene: 16160 Mouse
- SwissProt: P43431 Mouse
- SwissProt: P43432 Mouse
- Unigene: 103783 Mouse
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别名
- CLMF antibody
- CLMF p35 antibody
- CLMF p40 antibody
see all
实验方案
数据表及文件
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Datasheet download
文献 (2)
ab80682 被引用在 2 文献中.
- Yamaguchi T et al. Proinflammatory M1 Macrophages Inhibit RANKL-Induced Osteoclastogenesis. Infect Immun 84:2802-12 (2016). PubMed: 27456834
- Zhou X et al. Analysis of the direct injury effector of oligodendroglia cells or myelin sheath in an experimental allergic encephalomyelitis model induced by the MOG35-55 peptide. Mol Med Rep 12:7425-32 (2015). PubMed: 26459920