概述

  • 产品名称Anti-IL11RA抗体
    参阅全部 IL11RA 一抗
  • 描述
    兔多克隆抗体to IL11RA
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 177-370 of Human IL11RA (BC003110).

  • 阳性对照
    • Human fetal liver, heart, colon lysates, Human prostate carcinoma

性能

应用

Our Abpromise guarantee covers the use of ab109697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/2000. Predicted molecular weight: 45 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells.
  • 组织特异性Expressed in a number of cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma.
  • 序列相似性Belongs to the type I cytokine receptor family. Type 3 subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CRSDA antibody
    • hCG_2011440 antibody
    • I11RA_HUMAN antibody
    • IL-11 receptor subunit alpha antibody
    • IL-11R subunit alpha antibody
    • IL-11R-alpha antibody
    • IL-11RA antibody
    • IL11RA antibody
    • Interleukin 11 receptor alpha antibody
    • Interleukin 11 receptor alpha chain antibody
    • Interleukin-11 receptor subunit alpha antibody
    • MGC2146 antibody
    see all

Anti-IL11RA antibody 图像

  • All lanes : Anti-IL11RA antibody (ab109697) at 1/1000 dilution

    Lane 1 : Human fetal liver lysate
    Lane 2 : Human fetal heart lysate
    Lane 3 : Human fetal colon lysate


    Predicted band size : 45 kDa
  • ab109697 at 1/100 dilution staining IL11RA in Human prostate carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-IL11RA antibody (ab109697)参考文献

ab109697 has not yet been referenced specifically in any publications.

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