• 产品名称Anti-IL10RB抗体
    参阅全部 IL10RB 一抗
  • 描述
    兔多克隆抗体to IL10RB
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 21-218 of Human IL10RB (BC001903).

  • 阳性对照
    • Human fetal heart, liver, kidney and muscle lysates



Our Abpromise guarantee covers the use of ab106282 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
IHC-P Use at an assay dependent concentration.


  • 功能Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29.
  • 疾病相关Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) [MIM:612567]. It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.
  • 序列相似性Belongs to the type II cytokine receptor family.
    Contains 2 fibronectin type-III domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cd210 antibody
    • CDw210b antibody
    • CRF2 4 antibody
    • CRF2-4 antibody
    • CRFB4 antibody
    • Cytokine receptor class II antibody
    • Cytokine receptor class II CRF2 4 antibody
    • Cytokine receptor class-II member 4 antibody
    • Cytokine receptor family 2 member 4 antibody
    • Cytokine receptor family II member 4 antibody
    • D21S58 antibody
    • D21S66 antibody
    • I10R2_HUMAN antibody
    • IL-10 receptor subunit beta antibody
    • IL-10R subunit 2 antibody
    • IL-10R subunit beta antibody
    • IL-10R2 antibody
    • IL-10RB antibody
    • IL10R2 antibody
    • IL10RB antibody
    • Interleukin 10 receptor beta antibody
    • Interleukin-10 receptor subunit 2 antibody
    • Interleukin-10 receptor subunit beta antibody
    see all

Anti-IL10RB antibody 图像

  • All lanes : Anti-IL10RB antibody (ab106282) at 1/1000 dilution

    Lane 1 : Human fetal heart lysate
    Lane 2 : Human fetal liver lysate
    Lane 3 : Human fetal muscle lysate
    Lane 4 : Human fetal kidney lysate

    Predicted band size : 37 kDa

Anti-IL10RB antibody (ab106282)参考文献

ab106282 has not yet been referenced specifically in any publications.

Product Wall

Thank you for that extra information.

I look forward to hearing how you get on with the modifications I suggested. I would also add that performing a "no primary" control would probably be worthwhile doing as this would indicate if any of th...

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Thank you for contacting us and reporting the problems experienced when using anti-IL10RB antibody (ab106282).
I am sorry to hear that this antibody is not providing satisfactory results. The details provided will enable us to investigate this cas...

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