功能Receptor for IL10; binds IL10 with a high affinity.
组织特异性Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
疾病相关Inflammatory bowel disease 28
序列相似性Belongs to the type II cytokine receptor family.