Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Receptor for IL10; binds IL10 with a high affinity.
Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
Shi J et al. Anti-fibrotic actions of interleukin-10 against hypertrophic scarring by activation of PI3K/AKT and STAT3 signaling pathways in scar-forming fibroblasts. PLoS One9:e98228 (2014).
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