Anti-IL1 Receptor I抗体(ab106278)

概述

  • 产品名称Anti-IL1 Receptor I抗体
    参阅全部 IL1 Receptor I 一抗
  • 描述
    兔多克隆抗体to IL1 Receptor I
  • 经测试应用适用于: ICC/IF, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 18-241 of Human IL1 Receptor I (BC067506).

  • 阳性对照
    • Human fetal spleen lysate. HeLa cell lysate. Human fetal skin tissue.

性能

应用

Our Abpromise guarantee covers the use of ab106278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration. PubMed: 24950657
WB 1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 65 kDa).
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
  • 序列相似性Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Antigen CD121a antibody
    • CD121 antigen-like family member A antibody
    • CD121a antibody
    • CD121a antigen antibody
    • D2S1473 antibody
    • IL 1 antibody
    • IL 1R 1 antibody
    • IL 1R alpha antibody
    • IL 1RT1 antibody
    • IL-1R-1 antibody
    • IL-1R-alpha antibody
    • IL-1RT-1 antibody
    • IL-1RT1 antibody
    • IL1 inhibitor antibody
    • IL1R antibody
    • IL1R1 antibody
    • IL1R1_HUMAN antibody
    • IL1RA antibody
    • IL1RN antibody
    • IL1RT1 antibody
    • Interleukin 1 receptor alpha type 1 antibody
    • Interleukin 1 receptor antagonist protein (IRAP) antibody
    • Interleukin 1 receptor type I antibody
    • Interleukin receptor 1 antibody
    • Interleukin-1 receptor alpha antibody
    • Interleukin-1 receptor type 1 antibody
    • Interleukin-1 receptor type I antibody
    • p80 antibody
    see all

Anti-IL1 Receptor I antibody 图像

  • All lanes : Anti-IL1 Receptor I antibody (ab106278) at 1/500 dilution

    Lane 1 : Human fetal spleen lysate
    Lane 2 : HeLa cell lysate


    Predicted band size : 65 kDa
  • ab106278 staining interleukin 1 receptor 1 antibody in foetal epithelial skin tissue by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Antibody dilution 1/100.

Anti-IL1 Receptor I antibody (ab106278)参考文献

This product has been referenced in:
  • Oh YS  et al. Effects of bilateral vasectomy on the interleukin 1 system in mouse epididymis. Am J Reprod Immunol N/A:N/A (2016). IHC ; Mouse . Read more (PubMed: 27476761) »
  • Ma L  et al. Interleukin-1 beta guides the migration of cortical neurons. J Neuroinflammation 11:114 (2014). WB, IHC-FoFr, ICC/IF ; Rat . Read more (PubMed: 24950657) »

See all 2 Publications for this product

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ab106278 : sodium citrate buffer (10 mM Sodium citrate, pH 6.0), boil for 15 minutes.

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Colon, Dorsal Root Ganglia)
Specification Colon, Dorsal Root Ganglia
Fixative Paraformaldehyde
Permeabilization Yes - 0.2% Triton X-100
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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提交于 Oct 19 2011

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