概述

  • 产品名称Anti-IKB beta抗体
    参阅全部 IKB beta 一抗
  • 描述
    兔多克隆抗体to IKB beta
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide (Human). More details of the immunogen for this antibody are not available.

  • 阳性对照
    • Jurkat Cell Lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab42507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 38 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/1.77778.

靶标

  • 功能Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • 组织特异性Expressed in all tissues examined.
  • 序列相似性Belongs to the NF-kappa-B inhibitor family.
    Contains 6 ANK repeats.
  • 翻译后修饰Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • I kappa B beta antibody
    • I-kappa-B-beta antibody
    • IkappaBbeta antibody
    • IKB beta antibody
    • IkB-B antibody
    • IkB-beta antibody
    • IKBB antibody
    • IKBB_HUMAN antibody
    • IkBbeta antibody
    • NF kappa BIB antibody
    • NF-kappa-B inhibitor beta antibody
    • NF-kappa-BIB antibody
    • Nfkbib antibody
    • Thyroid receptor interacting protein 9 antibody
    • Thyroid receptor-interacting protein 9 antibody
    • TR interacting protein 9 antibody
    • TR-interacting protein 9 antibody
    • TRIP-9 antibody
    • TRIP9 antibody
    see all

Anti-IKB beta antibody 图像

  • All lanes : Anti-IKB beta antibody (ab42507) at 0.5 µg/ml

    Lane 1 : Marker
    Lane 2 : Jurkat Cell Lysate

    Secondary
    HRP conjugated anti-Rabbit IgG diluted 1:50,000-100,000

    Predicted band size : 38 kDa

Anti-IKB beta antibody (ab42507)参考文献

ab42507 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab42507.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"