概述

  • 产品名称Anti-IGLL1抗体
    参阅全部 IGLL1 一抗
  • 描述
    小鼠多克隆抗体to IGLL1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length IGLL1 protein (Human)

  • 阳性对照
    • Human kidney tissue lysate and 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab67081 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000.
    Detection Antibody Pair.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Critical for B-cell development.
    • 组织特异性Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).
    • 疾病相关Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2) [MIM:613500]. It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life.
    • 序列相似性Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 14.1 antibody
      • AGM2 antibody
      • CD179 antigen-like family member B antibody
      • CD179b antibody
      • CD179b antigen antibody
      • Ig lambda 5 antibody
      • Ig lambda-5 antibody
      • IGL1 antibody
      • IGL5 antibody
      • IGLJ14.1 antibody
      • IGLL antibody
      • Igll1 antibody
      • IGLL1_HUMAN antibody
      • IGO antibody
      • IGVPB antibody
      • Immunoglobulin lambda like polypeptide 1 precursor antibody
      • Immunoglobulin lambda-like polypeptide 1 antibody
      • Immunoglobulin omega polypeptide antibody
      • Immunoglobulin omega polypeptide chain antibody
      • Immunoglobulin related protein 14.1 antibody
      • Immunoglobulin-related protein 14.1 antibody
      • Lambda5 antibody
      • Pre B lymphocyte specific protein 2 antibody
      • VPREB2 antibody
      see all

    Anti-IGLL1 antibody 图像

    • Anti-IGLL1 antibody (ab67081) at 1/500 dilution + Human kidney tissue lysate at 25 µg/ml

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Observed band size : 29 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 58 kDa. We are unsure as to the identity of these extra bands.
    • All lanes : Anti-IGLL1 antibody (ab67081) at 1/500 dilution

      Lane 1 : IGLL1 transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg/ml per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Observed band size : 24 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 16 kDa. We are unsure as to the identity of these extra bands.

    Anti-IGLL1 antibody (ab67081)参考文献

    ab67081 has not yet been referenced specifically in any publications.

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