Anti-IGFBP3 (phospho S183)抗体(ab111931)

概述

  • 产品名称Anti-IGFBP3 (phospho S183)抗体
    参阅全部 IGFBP3 一抗
  • 描述
    兔多克隆抗体to IGFBP3 (phospho S183)
  • 特异性ab111931 detects endogenous levels of IGFBP3 only when phosphorylated at serine 183.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic phosphopeptide derived from Human IGFBP3 around the phosphorylation site of serine 183 (K-D-SP-Q-R).

  • 阳性对照
    • Human Brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab111931 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • 组织特异性Expressed by most tissues. Present in plasma.
  • 序列相似性Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • 发展阶段IGFBP3 levels are higher during extrauterine life and peak during puberty.
  • 结构域The thyroglobulin type-1 domain mediates interaction with HN.
  • 翻译后修饰Phosphorylation sites are present in the extracelllular medium.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acid stable subunit of the 140 K IGF complex antibody
    • Binding protein 29 antibody
    • Binding protein 53 antibody
    • BP 53 antibody
    • BP53 antibody
    • Growth hormone dependent binding protein antibody
    • IBP 3 antibody
    • IBP-3 antibody
    • IBP3 antibody
    • IBP3_HUMAN antibody
    • IGF binding protein 3 antibody
    • IGF-binding protein 3 antibody
    • IGFBP 3 antibody
    • IGFBP-3 antibody
    • IGFBP3 antibody
    • Insulin Like Growth Factor Binding Protein 3 antibody
    • Insulin-like growth factor binding protein 3 precursor antibody
    • Insulin-like growth factor-binding protein 3 antibody
    see all

Anti-IGFBP3 (phospho S183) antibody 图像

  • ab111931 at 1/50 dilution staining IGFBP3 in paraffin-embedded Human brain tissue by Immunohistochemistry. The image on the right is treated with the synthesized phosphopeptide.

Anti-IGFBP3 (phospho S183) antibody (ab111931)参考文献

ab111931 has not yet been referenced specifically in any publications.

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