Anti-IGFBP3抗体[RM0096-11B16] (ab86461)

概述

  • 产品名称Anti-IGFBP3抗体[RM0096-11B16]
    参阅全部 IGFBP3 一抗
  • 描述
    大鼠单克隆抗体[RM0096-11B16] to IGFBP3
  • 特异性No cross reactivity seen to other IGFBP proteins.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse recombinant IGFBP3.

  • 常规说明


    ab86461 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

性能

应用

Our Abpromise guarantee covers the use of ab86461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Use under non reducing condition. Predicted molecular weight: 32 kDa.

靶标

  • 功能IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • 组织特异性Expressed by most tissues. Present in plasma.
  • 序列相似性Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • 发展阶段IGFBP3 levels are higher during extrauterine life and peak during puberty.
  • 结构域The thyroglobulin type-1 domain mediates interaction with HN.
  • 翻译后修饰Phosphorylation sites are present in the extracelllular medium.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acid stable subunit of the 140 K IGF complex antibody
    • Binding protein 29 antibody
    • Binding protein 53 antibody
    • BP 53 antibody
    • BP53 antibody
    • Growth hormone dependent binding protein antibody
    • IBP 3 antibody
    • IBP-3 antibody
    • IBP3 antibody
    • IBP3_HUMAN antibody
    • IGF binding protein 3 antibody
    • IGF-binding protein 3 antibody
    • IGFBP 3 antibody
    • IGFBP-3 antibody
    • IGFBP3 antibody
    • Insulin Like Growth Factor Binding Protein 3 antibody
    • Insulin-like growth factor binding protein 3 precursor antibody
    • Insulin-like growth factor-binding protein 3 antibody
    see all

Anti-IGFBP3 antibody [RM0096-11B16] 图像

Anti-IGFBP3 antibody [RM0096-11B16] (ab86461)参考文献

ab86461 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"