Anti-IGFBP3抗体(ab109790)

概述

  • 产品名称Anti-IGFBP3抗体
    参阅全部 IGFBP3 一抗
  • 描述
    兔多克隆抗体to IGFBP3
  • 经测试应用适用于: Indirect ELISA, Sandwich ELISA, WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Highly pure (>98%) recombinant Human IGFBP3.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab109790 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Indirect ELISA Use a concentration of 0.5 - 2 µg/ml. (using 100 µl/well antibody solution) allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IGFBP3.
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to IGFBP3 (Biotin) (ab84228). Using ab84228 as the detection antibody and ab109790 as the capture antibody, the detection limit for recombinant Human IGFBP3 is 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 32 kDa. The detection limit for recombinant Human IGFBP3 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions

靶标

  • 功能IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • 组织特异性Expressed by most tissues. Present in plasma.
  • 序列相似性Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • 发展阶段IGFBP3 levels are higher during extrauterine life and peak during puberty.
  • 结构域The thyroglobulin type-1 domain mediates interaction with HN.
  • 翻译后修饰Phosphorylation sites are present in the extracelllular medium.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acid stable subunit of the 140 K IGF complex antibody
    • Binding protein 29 antibody
    • Binding protein 53 antibody
    • BP 53 antibody
    • BP53 antibody
    • Growth hormone dependent binding protein antibody
    • IBP 3 antibody
    • IBP-3 antibody
    • IBP3 antibody
    • IBP3_HUMAN antibody
    • IGF binding protein 3 antibody
    • IGF-binding protein 3 antibody
    • IGFBP 3 antibody
    • IGFBP-3 antibody
    • IGFBP3 antibody
    • Insulin Like Growth Factor Binding Protein 3 antibody
    • Insulin-like growth factor binding protein 3 precursor antibody
    • Insulin-like growth factor-binding protein 3 antibody
    see all

Anti-IGFBP3 antibody (ab109790)参考文献

ab109790 has not yet been referenced specifically in any publications.

Product Wall

Thank you for that clarification and sorry for the delay in my reply. The whole of the Scientific Support team were out for training yesterday so we are just catching up on enquiries now.

I have had a look through the experimental details you...

Read More

Thank you for getting back to me with your progress. I am sorry to hear the results are not as hoped for yet.

Thank you for providing the details of your experiment. I would like to clarify a few points to make sure I understand the experimen...

Read More

Thank you for your reply.

I would like to reassure you that ab83137 Anti-IGF1 antibody (Biotin) and ab9572 Anti-IGF1 antibody are tested and covered by our 6 month guarantee for sandwich ELISA together, and human samples. In the event that a...

Read More

Thank you for your reply.

I can confirm that ab84228 can be paired for Sandwich ELISA with Rabbit polyclonal to IGFBP3 (ab109790). I can suggest touse the polyclonal ab84228 as the detection antibody as this is the conjugated one (biotin con...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"