概述

  • 产品名称Anti-IGF2BP2抗体
    参阅全部 IGF2BP2 一抗
  • 描述
    兔多克隆抗体to IGF2BP2
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit, Horse, Cow, Dog, Pig, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 150-200 of Human IGF2BP2 according to NP_006539.3

  • 阳性对照
    • 293T whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab117827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-10 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs.
    • 组织特异性Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis.
    • 序列相似性Belongs to the RRM IMP/VICKZ family.
      Contains 4 KH domains.
      Contains 2 RRM (RNA recognition motif) domains.
    • 结构域The third and fourth KH domains are important for binding to the untranslated region (UTR) of target mRNA.
    • 细胞定位Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Hepatocellular carcinoma autoantigen p62 antibody
      • IF2B2_HUMAN antibody
      • IGF 2 mRNA binding protein 2 antibody
      • IGF II mRNA binding protein 2 antibody
      • IGF-II mRNA-binding protein 2 antibody
      • IGF2 mRNA-binding protein 2 antibody
      • Igf2bp2 antibody
      • IMP 2 antibody
      • IMP-2 antibody
      • IMP2 antibody
      • Insulin like growth factor 2 mRNA binding protein 2 antibody
      • Insulin-like growth factor 2 mRNA-binding protein 2 antibody
      • OTTHUMP00000082606 antibody
      • OTTHUMP00000082607 antibody
      • OTTHUMP00000082608 antibody
      • p62 antibody
      • VICKZ 2 antibody
      • VICKZ family member 2 antibody
      • VICKZ2 antibody
      see all

    Anti-IGF2BP2 antibody 图像

    • Detection of Human IGF2BP2 by Immunoprecipitation in 293T whole cell lysate (1 mg for IP, 20% of IP loaded) using ab117827 at 6 µg/mg of lysate. For subsequent WB detection, another anti Human IGF2BP2 antibody was used. Detection: Chemiluminescence with exposure time of 30 seconds.

    Anti-IGF2BP2 antibody (ab117827)参考文献

    ab117827 has not yet been referenced specifically in any publications.

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