Anti-IGF2抗体[MM0349-5L20] (ab89376)

概述

  • 产品名称Anti-IGF2抗体[MM0349-5L20]
    参阅全部 IGF2 一抗
  • 描述
    小鼠单克隆抗体[MM0349-5L20] to IGF2
  • 特异性ab89376 detects IGF2.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human) expressed in E. coli.

性能

应用

Our Abpromise guarantee covers the use of ab89376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 20 kDa.

靶标

  • 功能The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
    Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
  • 疾病相关Epigenetic changes of DNA hypomethylation in IGF2 are a cause of Silver-Russell syndrome (SIRS) [MIM:180860]. SIRS is a clinically heterogeneous condition characterized by severe intrauterine growth retardation, poor postnatal growth, craniofacial features such as a triangular shaped face and a broad forehead, body asymmetry, and a variety of minor malformations.
  • 序列相似性Belongs to the insulin family.
  • 翻译后修饰O-glycosylated with a core 1 or possibly core 8 glycan.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C11orf43 antibody
    • IGF 2 antibody
    • IGF II antibody
    • IGF-II antibody
    • IGF2 antibody
    • IGF2_HUMAN antibody
    • IGFII antibody
    • INSIGF antibody
    • insulin like growth factor 2 (somatomedin A) antibody
    • Insulin like Growth Factor 2 antibody
    • Insulin like growth factor II antibody
    • Insulin like growth factor II precursor antibody
    • Insulin like growth factor type 2 antibody
    • pp9974 antibody
    • Preptin antibody
    • putative insulin like growth factor II associated protein antibody
    • Somatomedin A antibody
    • Somatomedin-A antibody
    see all

Anti-IGF2 antibody [MM0349-5L20] (ab89376)参考文献

ab89376 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89376.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"