概述

  • 产品名称Anti-IgE抗体[4G7]
    参阅全部 IgE 一抗
  • 描述
    小鼠单克隆抗体[4G7] to IgE
  • 特异性This antibody reacts with human IgE. Specificity was confirmed by ELISA
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified) corresponding to Human IgE.

  • 常规说明This antibody recognizes an epitope different from the one recognized by ab774 and ab775.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度>95% by SDS-PAGE
  • 纯化说明Purified from ascites by DEAE chromatography and precipitation methods.
  • 克隆单克隆
  • 克隆编号4G7
  • 骨髓瘤unknown
  • 同种型IgG
  • 轻链类型unknown
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
  • 应用说明ELISA: Use at an assay dependant dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
    • 细胞定位Cell Membrane
    • 数据库链接
    • 别名
      • Igh2 antibody
      • IGHE antibody
      • IGHEP1 antibody
      • Immunoglobulin heavy constant epsilon antibody

    Anti-IgE antibody [4G7] (ab773)参考文献

    This product has been referenced in:
    • Mueller GA  et al. Hydrogen exchange nuclear magnetic resonance spectroscopy mapping of antibody epitopes on the house dust mite allergen Der p 2. J Biol Chem 276:9359-65 (2001). Read more (PubMed: 11134039) »
    • Smith AM  et al. The molecular basis of antigenic cross-reactivity between the group 2 mite allergens. J Allergy Clin Immunol 107:977-84 (2001). Read more (PubMed: 11398074) »

    See all 2 Publications for this product

    Product Wall

    Detailed epitope mapping was not performed (only cross-blocking studies with the three mAb to human IgE). Conjugates with HRP will be available, most probably will appear in the catalogue on September/October 2002. The preliminary studies showed that H...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"