概述

  • 产品名称Anti-IFT172抗体
  • 描述
    兔多克隆抗体to IFT172
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence, corresponding to internal sequence amino acids 1490-1599 of Human IFT172.

  • 阳性对照
    • Human lateral ventricle tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab122879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
  • 序列相似性Belongs to the IFT172 family.
    Contains 14 TPR repeats.
    Contains 9 WD repeats.
  • 细胞定位Cell projection > cilium.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IF172_HUMAN antibody
    • ift172 antibody
    • Intraflagellar transport 172 homolog (Chlamydomonas) antibody
    • Intraflagellar transport protein 172 homolog antibody
    • Osm 1 antibody
    • Selective LIM binding factor homolog antibody
    • SLB antibody
    • Wim antibody
    • Wimple homolog antibody
    see all

Anti-IFT172 antibody 图像

  • ab122879 at 1/50 dilution staining IFT172 in paraffin-embedded Human lateral ventricle tissue by Immunohistochemistry.

Anti-IFT172 antibody (ab122879)参考文献

This product has been referenced in:
  • Halbritter J  et al. Defects in the IFT-B Component IFT172 Cause Jeune and Mainzer-Saldino Syndromes in Humans. Am J Hum Genet 93:915-25 (2013). Human . Read more (PubMed: 24140113) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"