Anti-IFNAR1 (phospho S535 + S539)抗体(ab30571)

概述

  • 产品名称Anti-IFNAR1 (phospho S535 + S539)抗体
    参阅全部 IFNAR1 一抗
  • 描述
    兔多克隆抗体to IFNAR1 (phospho S535 + S539)
  • 特异性Specific for IFNAR1 protein phosphorylated at Ser535,539 in Western blots of human brain extracts.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-535,539 of human Interferon-alpha Receptor, Type I, Subunit I (IFNAR1).

性能

应用

Our Abpromise guarantee covers the use of ab30571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/1000. Predicted molecular weight: 110-130 kDa.
    Note: the molecular weight of the IFNNAR1 varies with cell line
    (different levels of glycosylation) in 293 and HeLa Cells; the mature form is ~110 - 130k.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
    • 组织特异性IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
    • 序列相似性Belongs to the type II cytokine receptor family.
      Contains 3 fibronectin type-III domains.
    • 翻译后修饰Phosphorylated on tyrosine residues by TYK2 tyrosine kinase.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Alpha type antiviral protein antibody
      • AVP antibody
      • Beta type antiviral protein antibody
      • CRF2-1 antibody
      • Cytokine receptor class-II member 1 antibody
      • Cytokine receptor family 2 member 1 antibody
      • IFN alpha REC antibody
      • IFN alpha receptor antibody
      • IFN alpha/beta Receptor alpha antibody
      • IFN beta receptor antibody
      • IFN-alpha/beta receptor 1 antibody
      • IFN-R-1 antibody
      • IFNAR antibody
      • Ifnar1 antibody
      • IFNBR antibody
      • IFRC antibody
      • INAR1_HUMAN antibody
      • Interferon (alpha beta and omega) receptor 1 antibody
      • Interferon alpha/beta receptor 1 antibody
      • Interferon alpha/beta receptor alpha chain antibody
      • Interferon beta receptor 1 antibody
      • Type I interferon receptor 1 antibody
      see all

    Anti-IFNAR1 (phospho S535 + S539) antibody 图像

    Anti-IFNAR1 (phospho S535 + S539) antibody (ab30571)参考文献

    ab30571 has not yet been referenced specifically in any publications.

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