概述

  • 产品名称
  • 描述
    兔多克隆抗体to IFNAR1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to a sequence within amino acids 3-210 of Human IFNAR1 (NP_000620).

  • 阳性对照
    • A431 whole cell lysates, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab97701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 64 kDa.

靶标

  • 功能
    Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
  • 组织特异性
    IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
  • 序列相似性
    Belongs to the type II cytokine receptor family.
    Contains 3 fibronectin type-III domains.
  • 翻译后修饰
    Phosphorylated on tyrosine residues by TYK2 tyrosine kinase.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha type antiviral protein antibody
    • Antiviral protein, alpha-type antibody
    • Antiviral protein, beta-type antibody
    • AVP antibody
    • Beta type antiviral protein antibody
    • CRF2-1 antibody
    • Cytokine receptor class-II member 1 antibody
    • Cytokine receptor family 2 member 1 antibody
    • IFN alpha REC antibody
    • IFN alpha receptor antibody
    • IFN alpha/beta Receptor alpha antibody
    • IFN beta receptor antibody
    • IFN Interferon-beta receptor antibody
    • IFN-alpha/beta receptor 1 antibody
    • IFN-R-1 antibody
    • IFNAR antibody
    • Ifnar1 antibody
    • IFNBR antibody
    • IFRC antibody
    • INAR1_HUMAN antibody
    • Interferon (alpha beta and omega) receptor 1 antibody
    • interferon alpha and beta receptor subunit 1 antibody
    • Interferon alpha/beta receptor 1 antibody
    • Interferon alpha/beta receptor alpha chain antibody
    • Interferon beta receptor 1 antibody
    • interferon receptor 1 antibody
    • Interferon-alpha receptor antibody
    • Type I interferon receptor 1 antibody
    see all

Anti-IFNAR1 antibody 图像

  • Anti-IFNAR1 antibody (ab97701) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 64 kDa

实验方案

Anti-IFNAR1 antibody (ab97701)参考文献

ab97701 has not yet been referenced specifically in any publications.

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