Anti-IFNAR1抗体(ab91466)

概述

  • 产品名称Anti-IFNAR1抗体
    参阅全部 IFNAR1 一抗
  • 描述
    兔多克隆抗体to IFNAR1
  • 特异性ab91466 recognises isoform 2
  • 经测试应用适用于: ELISA, Sandwich ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the center region of Human IFNAR1 conjugated to KLH (NP_000620.2).

  • 阳性对照
    • K562 cell line lysates.
  • 常规说明

    This antibody was used as a capture antibody in sELISA and was paired with ab10739 as detection antibody. Abreview 24657.

     

性能

应用

Our Abpromise guarantee covers the use of ab91466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
Sandwich ELISA
WB
  • 应用说明ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
    • 组织特异性IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
    • 序列相似性Belongs to the type II cytokine receptor family.
      Contains 3 fibronectin type-III domains.
    • 翻译后修饰Phosphorylated on tyrosine residues by TYK2 tyrosine kinase.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Alpha type antiviral protein antibody
      • AVP antibody
      • Beta type antiviral protein antibody
      • CRF2-1 antibody
      • Cytokine receptor class-II member 1 antibody
      • Cytokine receptor family 2 member 1 antibody
      • IFN alpha REC antibody
      • IFN alpha receptor antibody
      • IFN alpha/beta Receptor alpha antibody
      • IFN beta receptor antibody
      • IFN-alpha/beta receptor 1 antibody
      • IFN-R-1 antibody
      • IFNAR antibody
      • Ifnar1 antibody
      • IFNBR antibody
      • IFRC antibody
      • INAR1_HUMAN antibody
      • Interferon (alpha beta and omega) receptor 1 antibody
      • Interferon alpha/beta receptor 1 antibody
      • Interferon alpha/beta receptor alpha chain antibody
      • Interferon beta receptor 1 antibody
      • Type I interferon receptor 1 antibody
      see all

    Anti-IFNAR1 antibody 图像

    • Anti-IFNAR1 antibody (ab91466) at 1/100 dilution + K562 cell line lysates at 35 µg

      Predicted band size : 50 kDa

    Anti-IFNAR1 antibody (ab91466)参考文献

    ab91466 has not yet been referenced specifically in any publications.

    Product Wall

    Abreviews
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application ELISA
    Sample Human Recombinant protein (IFNAR1 Recombinant Protein and K562 cell lysates)
    Specification IFNAR1 Recombinant Protein and K562 cell lysates
    Blocking step BSA as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 0.05% · Temperature: 4°C
    Type Sandwich (Detection)
    Username

    Christopher Leung

    Verified customer

    提交于 Aug 12 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"