概述

  • 产品名称Anti-IDH3B抗体
    参阅全部 IDH3B 一抗
  • 描述
    兔多克隆抗体to IDH3B
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 90-378 of Human IDH3B (BC001960).

  • 阳性对照
    • Human placenta, fetal heart and Jurkat cell lysates; Human fetal skeletal muscle tissue.

性能

应用

Our Abpromise guarantee covers the use of ab112544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 42 kDa).
IHC-P 1/100 - 1/500.

靶标

  • 疾病相关Defects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • 序列相似性Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ11043 antibody
    • H-IDHB antibody
    • Idh3B antibody
    • IDH3B_HUMAN antibody
    • Isocitrate dehydrogenase [NAD] subunit beta antibody
    • Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial antibody
    • isocitrate dehydrogenase 3, beta subunit antibody
    • Isocitric dehydrogenase antibody
    • Isocitric dehydrogenase subunit beta antibody
    • MGC903 antibody
    • mitochondrial antibody
    • NAD(+)-specific ICDH antibody
    • NAD(+)-specific ICDH subunit beta antibody
    • NAD+-specific isocitrate dehydrogenase b subunit antibody
    • NAD+-specific isocitrate dehydrogenase beta antibody
    • OTTHUMP00000030023 antibody
    • OTTHUMP00000030024 antibody
    • RP46 antibody
    see all

Anti-IDH3B antibody 图像

  • All lanes : Anti-IDH3B antibody (ab112544) at 1/500 dilution

    Lane 1 : Human fetal heart lysate
    Lane 2 : Human placenta lysate
    Lane 3 : Jurkat cell lysate


    Predicted band size : 42 kDa
  • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human fetal skeletal muscle tissue, using ab112544 at 1/100 dilution. Note cytoplasmic staining.

Anti-IDH3B antibody (ab112544)参考文献

ab112544 has not yet been referenced specifically in any publications.

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