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ab55271 被引用在 11 文献中.

  • Terunuma A  et al. MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. J Clin Invest 124:398-412 (2014). WB . PubMed: 24316975
  • Akbay EA  et al. D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice. Genes Dev 28:479-90 (2014). WB . PubMed: 24589777
  • Ward PS  et al. The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization. J Biol Chem 288:3804-15 (2013). WB ; Human . PubMed: 23264629
  • Lu C  et al. Induction of sarcomas by mutant IDH2. Genes Dev 27:1986-98 (2013). PubMed: 24065766
  • Chen C  et al. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition. Genes Dev 27:1974-85 (2013). PubMed: 24065765
  • Lu C  et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 483:474-8 (2012). PubMed: 22343901
  • Grassian AR  et al. Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT). J Biol Chem 287:42180-94 (2012). WB ; Human . PubMed: 23038259
  • Black KM  et al. Microarray and proteomic analysis of the cardioprotective effects of cold blood cardioplegia in the mature and aged male and female. Physiol Genomics 44:1027-41 (2012). WB . PubMed: 22968637
  • Wise DR  et al. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of a-ketoglutarate to citrate to support cell growth and viability. Proc Natl Acad Sci U S A : (2011). WB ; Human . PubMed: 22106302
  • Ward PS  et al. The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting alpha-Ketoglutarate to 2-Hydroxyglutarate. Cancer Cell : (2010). WB ; Human . PubMed: 20171147
  • Dang L  et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462:739-44 (2009). WB ; Human . PubMed: 19935646

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