Anti-ICOS Ligand抗体[HK5.3] (Phycoerythrin) (ab93551)

概述

  • 产品名称Anti-ICOS Ligand抗体[HK5.3] (Phycoerythrin)
    参阅全部 ICOS Ligand 一抗
  • 描述
    大鼠单克隆抗体[HK5.3] to ICOS Ligand (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse B7-RP1 transfected cell line.

  • 阳性对照
    • BALB/c splenocytes.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号HK5.3
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab93551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use at a concentration of 0.06 µg/test.
    A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 105 to 108 cells/test.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
    • 组织特异性Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.
    • 序列相似性Belongs to the immunoglobulin superfamily. BTN/MOG family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B7 H2 antibody
      • B7 homolog 2 antibody
      • B7 homologue 2 antibody
      • B7 like protein Gl50 antibody
      • B7 related protein 1 antibody
      • B7-H2 antibody
      • B7-like protein Gl50 antibody
      • B7-related protein 1 antibody
      • B7H2 antibody
      • B7RP 1 antibody
      • B7RP-1 antibody
      • B7RP1 antibody
      • CD 275 antibody
      • CD275 antibody
      • CD275 antigen antibody
      • GL 50 antibody
      • GL50 antibody
      • ICOS L antibody
      • ICOS LG antibody
      • ICOS ligand antibody
      • ICOSL antibody
      • ICOSL_HUMAN antibody
      • Icoslg antibody
      • Inducible T cell co stimulator ligand antibody
      • KIAA0653 antibody
      • LICOS antibody
      • Transmembrane protein B7 H2 ICOS ligand antibody
      see all

    Anti-ICOS Ligand antibody [HK5.3] (Phycoerythrin) 图像

    • ab93551 at 0.06µg dilution staining ICOS Ligand in BALB/c splenocytes by Flow Cytometry.

    Anti-ICOS Ligand antibody [HK5.3] (Phycoerythrin) (ab93551)参考文献

    ab93551 has not yet been referenced specifically in any publications.

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