Anti-ICOS Ligand抗体(ab88343)


  • 产品名称Anti-ICOS Ligand抗体
    参阅全部 ICOS Ligand 一抗
  • 描述
    小鼠单克隆抗体to ICOS Ligand
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 20-302 of Human ICOS Ligand (AAH64637) with a 26 kDa proprietary tag.

  • 阳性对照
    • Partial recombinant tagged ICOS Ligand protein (immunogen). HL60 cell lysate.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域


Our Abpromise guarantee covers the use of ab88343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 34 kDa (predicted molecular weight: 34 kDa).
ELISA Use at an assay dependent dilution. Detection limit for recombinant tagged ICOS Ligand protein is approximately 0.03ng/ml as a capture antibody.


  • 功能Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
  • 组织特异性Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.
  • 序列相似性Belongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B7 H2 antibody
    • B7 homolog 2 antibody
    • B7 homologue 2 antibody
    • B7 like protein Gl50 antibody
    • B7 related protein 1 antibody
    • B7-H2 antibody
    • B7-like protein Gl50 antibody
    • B7-related protein 1 antibody
    • B7H2 antibody
    • B7RP 1 antibody
    • B7RP-1 antibody
    • B7RP1 antibody
    • CD 275 antibody
    • CD275 antibody
    • CD275 antigen antibody
    • GL 50 antibody
    • GL50 antibody
    • ICOS L antibody
    • ICOS LG antibody
    • ICOS ligand antibody
    • ICOSL antibody
    • ICOSL_HUMAN antibody
    • Icoslg antibody
    • Inducible T cell co stimulator ligand antibody
    • KIAA0653 antibody
    • LICOS antibody
    • Transmembrane protein B7 H2 ICOS ligand antibody
    see all

Anti-ICOS Ligand antibody 图像

  • Anti-ICOS Ligand antibody (ab88343) at 1 µg/ml + Partial recombinant tagged ICOS Ligand protein (immunogen) at 0.2 µg

    Goat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

    Predicted band size : 34 kDa
    Observed band size : 57 kDa (why is the actual band size different from the predicted?)
  • Anti-ICOS Ligand antibody (ab88343) at 1 µg/ml + HL60 cell lysate at 25 µg

    Goat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

    Predicted band size : 34 kDa
    Observed band size : 34 kDa

Anti-ICOS Ligand antibody (ab88343)参考文献

ab88343 has not yet been referenced specifically in any publications.

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