Anti-ICOS Ligand抗体(ab123554)

概述

  • 产品名称Anti-ICOS Ligand抗体
    参阅全部 ICOS Ligand 一抗
  • 描述
    兔多克隆抗体to ICOS Ligand
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 216-246 of Human ICOS Ligand (NP_056074.1).

  • 阳性对照
    • HL60 cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab123554 was purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 33 kDa.

靶标

  • 功能Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
  • 组织特异性Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.
  • 序列相似性Belongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B7 H2 antibody
    • B7 homolog 2 antibody
    • B7 homologue 2 antibody
    • B7 like protein Gl50 antibody
    • B7 related protein 1 antibody
    • B7-H2 antibody
    • B7-like protein Gl50 antibody
    • B7-related protein 1 antibody
    • B7H2 antibody
    • B7RP 1 antibody
    • B7RP-1 antibody
    • B7RP1 antibody
    • CD 275 antibody
    • CD275 antibody
    • CD275 antigen antibody
    • GL 50 antibody
    • GL50 antibody
    • ICOS L antibody
    • ICOS LG antibody
    • ICOS ligand antibody
    • ICOSL antibody
    • ICOSL_HUMAN antibody
    • Icoslg antibody
    • Inducible T cell co stimulator ligand antibody
    • KIAA0653 antibody
    • LICOS antibody
    • Transmembrane protein B7 H2 ICOS ligand antibody
    see all

Anti-ICOS Ligand antibody 图像

  • Anti-ICOS Ligand antibody (ab123554) at 1/100 dilution + HL60 cell lysate at 35 µg

    Predicted band size : 33 kDa

Anti-ICOS Ligand antibody (ab123554)参考文献

ab123554 has not yet been referenced specifically in any publications.

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