Anti-ICOS抗体[7E.17G9] (ab95630)
Key features and details
- Rat monoclonal [7E.17G9] to ICOS
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2b
概述
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产品名称
Anti-ICOS抗体[7E.17G9]
参阅全部 ICOS 一抗 -
描述
大鼠单克隆抗体[7E.17G9] to ICOS -
宿主
Rat -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Mouse ICOS cDNA and ICOS hexahistidine fusion protein.
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阳性对照
- Three day ConA activated BALB/c splenocytes or Mouse splenocyte suspensions
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
7E.17G9 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95630于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt |
Use 0.06-1µg for 105-8 cells.
A 100 µl volume is recommended for staining the cell sample.
ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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说明 |
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Flow Cyt
Use 0.06-1µg for 105-8 cells. A 100 µl volume is recommended for staining the cell sample.
ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
|
靶标
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功能
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. -
组织特异性
Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B-cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newborn thymus. -
疾病相关
Immunodeficiency, common variable, 1 -
序列相似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻译后修饰
N-glycosylated. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 54167 Mouse
- SwissProt: Q9WVS0 Mouse
- Unigene: 42044 Mouse
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别名
- Activation inducible lymphocyte immunomediatory molecule antibody
- Activation-inducible lymphocyte immunomediatory molecule antibody
- AILIM antibody
see all
图片
数据表及文件
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Datasheet download
文献 (0)
ab95630 尚未被引用在任何文献中。