概述

  • 产品名称
  • 描述
    山羊多克隆抗体to ICAM5
  • 经测试应用
    适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    C-ESPAEGEVFAIQ

    , corresponding to C terminal amino acids 909-920 of Human ICAM5

  • 阳性对照
    • Lysates of Human brain - frontal cortex and hippocampus. Mouse brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab53561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/32000.
IHC-P Use a concentration of 2 - 4 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 相关性
    ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
  • 细胞定位
    Membrane; single-pass type I membrane protein
  • 数据库链接
  • 别名
    • ICAM5 precursor antibody
    • Intercellular adhesion molecule 5 antibody
    • Intercellular adhesion molecule 5 precursor antibody
    • Intercellular adhesion molecule 5, telencephalin antibody
    • Telencephalin antibody
    • TLCN antibody
    • TLN antibody
    see all

图片

  • ab53561 at 2.5µg/ml staining human brain (cerebral cortex) tissue sections by immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections). The tissue sections subjected to antigen retrieval by steam with citrate buffer. The AP-staining staining procedure was used for detection.

文献

ab53561 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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