Anti-ICAM2抗体[mIC2/4 (3C4)] (Biotin) (ab33703)

概述

  • 产品名称
    Anti-ICAM2抗体[mIC2/4 (3C4)] (Biotin)
    参阅全部 ICAM2 一抗
  • 描述
    大鼠单克隆抗体[mIC2/4 (3C4)] to ICAM2 (Biotin)
  • 偶联物
    Biotin
  • 特异性
    Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1.
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Tissue/ cell preparation. COS cells transfected with murine ICAM-2.

  • 常规说明


    Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA1.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituents: PBS, 1% BSA
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
  • Primary antibody说明
    Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA1.
  • 克隆
    单克隆
  • 克隆编号
    mIC2/4 (3C4)
  • 骨髓瘤
    P3x63-Ag8.653
  • 同种型
    IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab33703 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/1 - 1/5.

Use 10µl of suggested working dilution to label 106 cells.





ab18445-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性
    ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
  • 细胞定位
    Membrane; Single-pass type I membrane protein
  • 数据库链接
  • 别名
    • CD102 antibody
    • CD102 antigen antibody
    • ICAM 2 antibody
    • Intercellular adhesion molecule 2 antibody
    • Ly60 antibody
    see all

文献

This product has been referenced in:
  • Soede RD  et al. LFA-1 to LFA-1 signals involve zeta-associated protein-70 (ZAP-70) tyrosine kinase: relevance for invasion and migration of a T cell hybridoma. J Immunol 163:4253-61 (1999). Read more (PubMed: 10510363) »
  • Xu H  et al. Characterization of murine intercellular adhesion molecule-2. J Immunol 156:4909-14 (1996). Read more (PubMed: 8648141) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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