Anti-ICAM1 (phospho Y512)抗体(ab51033)

概述

  • 产品名称Anti-ICAM1 (phospho Y512)抗体
    参阅全部 ICAM1 一抗
  • 描述
    兔多克隆抗体to ICAM1 (phospho Y512)
  • 特异性The antibody detects endogenous levels of ICAM-1 only when phosphorylated at tyrosine 512.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    The antiserum was produced against synthesised phosphopeptide derived from ICAM-1 around the phosphorylation site of tyrosine 512 (K-K-YP-R-L)(Human)

性能

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应用

Our Abpromise guarantee covers the use of ab51033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 96 kDa (predicted molecular weight: 58 kDa).
ELISA 1/40000.

靶标

  • 功能ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
  • 序列相似性Belongs to the immunoglobulin superfamily. ICAM family.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
  • 翻译后修饰Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Antigen identified by monoclonal antibody BB2 antibody
    • BB 2 antibody
    • BB2 antibody
    • CD 54 antibody
    • CD_antigen=CD54 antibody
    • CD54 antibody
    • Cell surface glycoprotein P3.58 antibody
    • Human rhinovirus receptor antibody
    • ICAM 1 antibody
    • ICAM-1 antibody
    • ICAM1 antibody
    • ICAM1_HUMAN antibody
    • intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody
    • Intercellular adhesion molecule 1 antibody
    • Major group rhinovirus receptor antibody
    • MALA 2 antibody
    • MALA2 antibody
    • MyD 10 antibody
    • MyD10 antibody
    • P3.58 antibody
    • Surface antigen of activated B cells, BB2 antibody
    see all

Anti-ICAM1 (phospho Y512) antibody 图像

  • All lanes : Anti-ICAM1 (phospho Y512) antibody (ab51033) at 1/500 dilution

    Lane 1 : Hela cells treated with TNF alpha with immunizing peptide
    Lane 2 : Hela cells treated with TNF alpha


    Predicted band size : 58 kDa
    Observed band size : 96 kDa (why is the actual band size different from the predicted?)

Anti-ICAM1 (phospho Y512) antibody (ab51033)参考文献

ab51033 has not yet been referenced specifically in any publications.

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