Anti-ICAM1抗体[HM1] (ab7222)

概述

  • 产品名称Anti-ICAM1抗体[HM1]
    参阅全部 ICAM1 一抗
  • 描述
    小鼠单克隆抗体[HM1] to ICAM1
  • 经测试应用适用于: IHC-Fr, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein (Human).

性能

应用

Our Abpromise guarantee covers the use of ab7222 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr
ICC/IF
  • 应用说明The antibody is useful for staining of in vitro cultured cells and for staining of frozen sections by means of immunofluorescence and immunohistochemistry.
    In vitro cultured cells can be fixed with 1% paraformaldehyde and kept in PBS plus azide before staining.
  • 靶标

    • 功能ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
    • 序列相似性Belongs to the immunoglobulin superfamily. ICAM family.
      Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    • 翻译后修饰Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Antigen identified by monoclonal antibody BB2 antibody
      • BB 2 antibody
      • BB2 antibody
      • CD 54 antibody
      • CD_antigen=CD54 antibody
      • CD54 antibody
      • Cell surface glycoprotein P3.58 antibody
      • Human rhinovirus receptor antibody
      • ICAM 1 antibody
      • ICAM-1 antibody
      • ICAM1 antibody
      • ICAM1_HUMAN antibody
      • intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody
      • Intercellular adhesion molecule 1 antibody
      • Major group rhinovirus receptor antibody
      • MALA 2 antibody
      • MALA2 antibody
      • MyD 10 antibody
      • MyD10 antibody
      • P3.58 antibody
      • Surface antigen of activated B cells, BB2 antibody
      see all

    Anti-ICAM1 antibody [HM1] (ab7222)参考文献

    ab7222 has not yet been referenced specifically in any publications.

    Product Wall

    This antibody works in frozen sections. We have not tried it in paraffin sections yet.

    We did a search on medline for ICAM-1 AND HM1 but could not find a specific reference to this antibody. Please let us know if you can find one or if you publish with it.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"