概述

  • 产品名称Anti-ICAD抗体
    参阅全部 ICAD 一抗
  • 描述
    兔多克隆抗体to ICAD
  • 特异性Detects endogenous levels of total ICAD protein.
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide (Human) from an internal region

  • 阳性对照
    • Human breast carcinoma tissue 293, Jurkat cell and HeLa cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab65129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

靶标

  • 功能Inhibitor of the caspase-activated DNase (DFF40).
  • 序列相似性Contains 1 CIDE-N domain.
  • 翻译后修饰Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A330085O09Rik antibody
    • Caspase activated deoxyribonuclease inhibitor short form antibody
    • DFF 1 antibody
    • DFF 45 antibody
    • DFF alpha antibody
    • DFF-45 antibody
    • DFF1 antibody
    • DFF35 antibody
    • DFF45 antibody
    • DFFA antibody
    • Dffa DNA fragmentation factor, alpha subunit antibody
    • DFFA_HUMAN antibody
    • DNA fragmentation factor 45 kDa subunit antibody
    • DNA Fragmentation Factor Alpha Subunit antibody
    • DNA fragmentation factor subunit alpha antibody
    • DNA fragmentation factor, 45 kD, alpha subunit antibody
    • DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1 antibody
    • DNA fragmentation factor, 45kDa, alpha polypeptide antibody
    • DNA fragmentation factor, alpha subunit antibody
    • DNAation factor 45 kDa subunit antibody
    • H13 antibody
    • ICAD antibody
    • ICAD L antibody
    • ICAD S antibody
    • Inhibitor of CAD antibody
    • Inhibitor of Caspase Activated DNase antibody
    • MGC143066 antibody
    • OTTHUMP00000001903 antibody
    • OTTHUMP00000001904 antibody
    • RP23 121D17.3 antibody
    see all

Anti-ICAD antibody 图像

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue labelled with ab65129 at 1/50 dilution. The right hand panel was also treated with immunising peptide.
  • All lanes : Anti-ICAD antibody (ab65129) at 1/500 dilution

    Lane 1 : 293 cell extract
    Lane 2 : Jurkat cell extract
    Lane 3 : HeLa cell extract
    Lane 4 : HeLa cell extract with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 37 kDa
    Observed band size : 37 kDa
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

Anti-ICAD antibody (ab65129)参考文献

ab65129 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab65129.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"