• 产品名称Anti-HYPE抗体
    参阅全部 HYPE 一抗
  • 描述
    兔多克隆抗体to HYPE
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 409-458 (GDVRPFIRFI AKCTETTLDT LLFATTEYSV ALPEAQPNHS GFKETLPVKP) of Human HYPE (NP_009007).

  • 阳性对照
    • 293T cells transfected with HYPE cell lysate. Human muscle.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab104763 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.25 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • 功能Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the fic family.
    Contains 1 fido domain.
    Contains 2 TPR repeats.
  • 结构域The fido domain mediates the adenylyltransferase activity.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adenosine monophosphate-protein transferase FICD antibody
    • AMPylator FICD antibody
    • FIC domain containing antibody
    • FIC domain containing protein antibody
    • FIC domain-containing protein antibody
    • Fic S phase protein cell division homolog antibody
    • ficd antibody
    • FICD_HUMAN antibody
    • HIP-13 antibody
    • HIP13 antibody
    • Huntingtin interacting protein 13 antibody
    • Huntingtin interacting protein E antibody
    • Huntingtin interactor protein E antibody
    • Huntingtin yeast partner E antibody
    • Huntingtin-interacting protein 13 antibody
    • Huntingtin-interacting protein E antibody
    • MGC5623 antibody
    • UNQ3041 antibody
    see all

Anti-HYPE antibody 图像

  • Anti-HYPE antibody (ab104763) at 0.25 µg/ml + transfected 293T cell lysate at 10 µg

    Predicted band size : 52 kDa
    12% gel
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human muscle tissue labelling HYPE with ab104763 at 4-8µg/ml. Arrows indicate positively labelled skeletal muscle cells. Magnification: 400X.

Anti-HYPE antibody (ab104763)参考文献

ab104763 has not yet been referenced specifically in any publications.

Product Wall

Thanks for the additional details.

What speices of HYPE is your construct based on?

Thanks for your enquiry.

Just to confirm, ab104782 has been raised against a synthetic peptide immunogen "corresponding to a region within the C terminal amino acids 351-400". This peptide is a 15-20 amino acid peptide found withina...

Read More