概述

  • 产品名称Anti-HURP抗体
    参阅全部 HURP 一抗
  • 描述
    兔多克隆抗体to HURP
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (HKEYERNRHF GLKDVNIPTL EGRILVELDE TSQELVPEKT NVKPRAMKTI) of Human HURP (NP_055565)

  • 阳性对照
    • Transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab80684 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 94 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
  • 组织特异性Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.
  • 序列相似性Belongs to the SAPAP family.
  • 发展阶段Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells.
  • 翻译后修饰Ubiquitinated, leading to its degradation.
    Phosphorylated upon DNA damage, probably by ATM or ATR. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.
  • 细胞定位Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DAP-5 antibody
    • DAP5 antibody
    • Discs large homolog 7 antibody
    • Disks large associated protein 5 antibody
    • Disks large associated protein DLG7 antibody
    • Disks large-associated protein 5 antibody
    • Disks large-associated protein DLG7 antibody
    • DLG 1 antibody
    • DLG 7 antibody
    • DLG1 antibody
    • DLG7 antibody
    • DLGAP5 antibody
    • DLGP5_HUMAN antibody
    • Drosophila discs large 1 tumor suppressor like antibody
    • Hepatoma up regulated protein antibody
    • Hepatoma up-regulated protein antibody
    • Hepatoma upregulated protein antibody
    • HURP antibody
    • KIAA0008 antibody
    see all

Anti-HURP antibody 图像

  • Anti-HURP antibody (ab80684) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µg

    Secondary
    HRP-conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 94 kDa
    Observed band size : 94 kDa

Anti-HURP antibody (ab80684)参考文献

ab80684 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab80684.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"